Non-invasive analyte measurement device having increased signal to noise ratios
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United States of America Patent
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Issued Date -
Nov 11, 2004
app pub date -
May 9, 2003
filing date -
May 9, 2003
priority date (Note) -
Abandoned
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Abstract
A non-invasive analyte measurement device having increased signal to noise ratios is disclosed herein. Typically, the glucose measurement device is self-normalizing in that it does not employ an independent reference sample in its operation. The device uses attenuated total reflection (ATR) infrared spectroscopy. The device is used on a fingertip and compares two specific regions of a measured infrared spectrum to determine the blood glucose level of the user. This device is suitable for monitoring glucose levels in the human body and is especially beneficial to users having diabetes mellitus. Moreover, the device utilizes a periodically modulated optical signal and at least one lock-in amplifier to correlate the signals to gain maximum sensitivity and an increased signal-to-noise ratio. The device and procedure can be used for other analyte materials which exhibit unique mid-IR signatures of the type described herein and that are found in appropriate regions of the outer skin.
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