Antibodies against SLC15A2 and uses thereof
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United States of America Patent
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Issued Date -
Nov 11, 2004
app pub date -
Feb 27, 2004
filing date -
Feb 28, 2003
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Abstract
The invention relates to the identification and generation of antibodies that specifically bind to SLC15A2 protein. The disclosed anti-SLC15A2 antibodies and compositions comprising them may be used for diagnosis, prognosis and therapy of cancer (including metastatic cancer) or fibrotic conditions, e.g., ovarian cancer, cervical cancer, prostate cancer, uterine cancer, lung cancer, lung fibrosis, and glioblastoma. The disclosed antibodies include conjugates with cytotoxic effector components that are useful for cancer therapy.
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