Novel form of the PHGPx protein as a diagnostic marker for male infertility

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United States of America Patent

SERIAL NO

10636796

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Abstract

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This invention relates to a novel form of the PHGPx protein, the sperm nuclei glutathione peroxidase (snGPx) as well as portions thereof playing a role in mammalian spermatogenesis, and to the nucleic acids encoding the same. The invention further relates to vectors containing said nucleic acid and to host cells transformed by these vectors. Furthermore the invention comprises antibodies specific for the above proteins/peptides as well as the use of the proteins/peptides in the diagnosis or therapy of male infertility.

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Patent Owner(s)

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GSF-FORSCHUNGSZENTRUM FUR UMWELT UND GESUNDHEIT GMBH85764 OBERSCHLEISSHEIM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Behne, Dietrich Berlin, DE 1 0
Bornkamm, Georg Munchen, DE 5 106
Brielmeier, Markus Garching, DE 6 67
Conrad, Marcus Munchen, DE 5 8
Kyriakopoulos, Antonios Berlin, DE 3 1
Pfeifer, Henning Berlin, DE 1 0
Schmidt, Jorg Munchen, DE 18 1329

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