Polyprolyl inhibitors of cyclophilin
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United States of America Patent
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Issued Date -
Oct 14, 2004
app pub date -
Apr 11, 2003
filing date -
Apr 11, 2003
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Abandoned
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Abstract
This invention relates to neurotrophic low molecular weight, small molecule peptidic cyclophilin inhibitor compounds having an affinity for cyclophilin-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
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