Means for inhibiting proteolytical processing of parkin
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United States of America Patent
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Issued Date -
Oct 7, 2004
app pub date -
Apr 12, 2004
filing date -
Mar 29, 2001
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Abandoned
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Abstract
An isolated nucleic acid sequence encoding a polypeptide functionally homologous to the wild type form of the Parkin polypeptide or a fragment of said polypeptide, the amino acid sequence of said polypeptide differing from the wild type amino acid sequence at least in including a mutation at Asp 126, wherein the said nucleic acid sequence is at least 70% identical to a nucleic acid sequence encoding the wild type Parkin polypeptide, and a mutated Parkin polypeptide.
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