Neutron capture therapy
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United States of America Patent
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Issued Date -
Sep 16, 2004
app pub date -
May 4, 2004
filing date -
May 25, 2001
priority date (Note) -
Abandoned
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Abstract
The present invention relates to immunoconjugates for use in neutron capture therapy, in particular Boron neutron capture therapy, for killing target cells such as tumours. The immunoconjugate of the invention comprises a monoclonal antibody having an affinity of at least 10.sup.11 l/mol and a cross-reactivity of less than 10%, and a neutron capture agent. More preferably, the affinity of the monoclonal antibody is at least 10.sup.12 l/mol.
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