Method for producing optical-active cis-piperidine derivatives
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United States of America Patent
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Issued Date -
Sep 2, 2004
app pub date -
Jan 12, 2004
filing date -
Dec 21, 2001
priority date (Note) -
Abandoned
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Abstract
An optical-active cis-piperidine derivative of high chemical purity and high optical purity is efficiently produced through optical resolution of a cis-piperidine derivative mixture, racemic cis-piperidine derivative with an optical-active tartaric acid derivative or an optical-active amino acid derivative. For the optical-active tartaric acid derivative, preferred are optical-active di(paratoluoyl)tartaric acid and optical-active di(4-methoxybenzoyl)tartaric acid; and for the optical-active amino acid derivative, preferred is optical-active N-benzenesulfonylphenylalanine.
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