Compositions and methods for high-level, large-scale production of recombinant proteins

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United States of America Patent

APP PUB NO 20040161817A1
SERIAL NO

10163863

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Compositions and methods for the high-level, large-scale production of recombinant proteins are disclosed. Illustrative compositions comprise one or more expression vectors capable of high-level protein and/or polypeptide expression in combination with an immortalized host cell-line capable of growth in serum-free, suspension culture. Bi-directional UCOE vectors that permit the simultaneous, high-level expression of two or more recombinant proteins and/or polypeptides from a single UCOE based plasmid vector.

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Patent Owner(s)

Patent OwnerAddress
CORIXA CORPORATIONSUITE 200 1124 COLUMBIA STREET SEATTLE WA 98104

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Bebbington, Christopher Robert San Mateo, CA 40 533
Benton, Trish Moss Beach, CA 1 33
Crombie, Robert Barbridge, GB 8 66
Henning, Karla Ann Burlingame, CA 5 35
King, David J Belmont, CA 68 1246
Shao, Xiang Santa Clara, CA 20 108

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