Transgenic mouse having conditional knock-out of myostatin function
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United States of America Patent
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Issued Date -
Aug 12, 2004
app pub date -
Feb 6, 2003
filing date -
Feb 6, 2003
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Abstract
The present invention involves carrying out a gene targeting method utilizing the cre-lox system in order to generate transgenic mice allowing for conditional inactivation of the myostatin gene. The transgenic mice of the present invention that express a conditionally inactivated myostatin gene also exhibit a phenotype characterized by skeletal muscle hypertrophy.
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