Photochemotherapeutic method using 5-aminolevulinic acid and other precursors of endogenous porphyrins
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United States of America Patent
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Sep 17, 2003
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Jul 28, 1989
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Abstract
Methods of detecting and treating rapidly growing exogenous cells, such as Protista, or parasites, that preferentially accumulate a photoactivatable porphyrin in which 5-aminolevulinic acid or precursor thereof is administered to the patient, or contacted to the exogenous cells, in an amount sufficient to induce synthesis fluorescence and/or photosensitizing concentrations of a protoporphyrin IX in the exogenous cells, followed by exposure of the exogenous cells to light of photoactivating wavelengths.
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