Neo-cartilage constructs and a method for preparation thereof

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United States of America Patent

SERIAL NO

10625245

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Abstract

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Neo-cartilage constructs suitable for implantation into a joint cartilage lesion in situ and a method for repair and restoration of function of injured, traumatized, aged or diseased cartilage. The construct comprises at least chondrocytes incorporated into a support matrix processed according to the algorithm comprising variable hydrostatic or atmospheric pressure or non-pressure conditions, variable rate of perfusion, variable medium composition, variable temperature, variable cell density and variable time to which the chondrocytes are subjected.

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Patent Owner(s)

Patent OwnerAddress
TAKAGI INDUSTRIAL CO LTD201 NISHIKASHIBARASHINDEN FUJI-SHI SHIZUOKA-KEN 417-8505
HISTOGENICS CORPORATION830 WINTER STREET 3RD FLOOR WALTHAM MA 02451

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Kusanagi, Akihiko Brookline, MA 27 757
Mizuno, Shuichi Brookline, MA 22 607
Smith, Robert Lane Palo Alto, CA 30 616
Tarrant, Laurence J B Easthampton, MA 26 711
Tokuno, Toshimasa Tokyo, JP 14 477

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