Bioavailable fenofibrate compositions, methods for treating hyperlipidemia and hypercholesterolemia and processes for the preparation of such compositions
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United States of America Patent
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Issued Date -
Jul 22, 2004
app pub date -
Jan 16, 2003
filing date -
Jan 16, 2003
priority date (Note) -
Abandoned
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Abstract
Pharmaceutical compositions for treating hyperlipidemia or hypercholesterolemia in mammals are described which comprise:1 (a) fenofibrate 5 to 35 wt. -% (b) a cyclodextrin 4 to 30 wt. -% (c) an alkali metal or 0.1 to 10 wt. -%; and alkaline earth metal docusate and/or alkali metal or alkaline earth metal lauryl sulfate (d) a water-insoluble, wettable 5 to 30 wt. -% inorganic carrier capable of forming a dispersion of the fenofibrate and a pharmaceutically acceptable inert carrier or diluent. A therapeutically effective amount of the compositions are orally administered to mammals to treat hyperlipidemia or hypercholesterolemia.
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