Ampk-related serine/threonine kinase, designated snark

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United States of America Patent

APP PUB NO 20040132025A1
SERIAL NO

10343514

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The cloning and function of a new AMPK-related kinase, designated SNARK, are described. The kinase SNARK is involved in the stress response to glucose deprivation. Provided are the rodent and human genes encoding SNARK, and the SNARK protein and useful fragments, in isolated form. Also provided are SNARK expression systems and assays useful to identify SNARK substrates and SNARK activity modulators, and antibodies useful as SNARK modulators for instance in therapeutic applications to modulate the metabolism of glucose.

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Patent OwnerAddress
1149336 ONTARIO INCTORONTO ONTARIO M6B 3G3

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Drucker, Daniel J Toronto, CA 38 896
Lefebvre, Diana L Mississauga, CA 1 0
Rosen, Cherly F Toronto, CA 1 0

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