Methods of performing medical procedures which promote bone growth, compositions which promote bone growth, and methods of making such compositions
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United States of America Patent
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Issued Date -
Jul 1, 2004
app pub date -
Mar 24, 2003
filing date -
Mar 22, 2002
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Abandoned
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Abstract
In an exemplary embodiment of the present invention, a method of performing a medical procedure includes the step of applying a particular material to a portion of a bone of a mammal. The particular material includes at least one glyceride and stimulates bone growth. For example, cyclic adenosine monophosphate regulated lipases may metabolize the particular material after the particular material is applied to the bone. The at least one glyceride of the particular material and water within the mammal then may be converted into glycerol, fatty acid, and protons, which stimulates a conversion of osteoprogenitor cells into osteoblast cells. Subsequently, the glycerol and the fatty acid may be oxidized, and the oxidation may stimulate the conversion of adenosine diphosphate within the mammal into adenosine triphosphate. The osteoblast cells then may convert the adenosine triphosphate into adenosine diphosphate, such that energy is released. Moreover, the osteoblast cells use the energy to synthesize at least Type-I collagen proteins within the mammal, which creates the bone growth.
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