Method for the production of (1S, 4R)-(-)-4-hydroxy cyclopent-2-enyl esters
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United States of America Patent
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Issued Date -
Jul 1, 2004
app pub date -
Dec 12, 2003
filing date -
Dec 13, 2002
priority date (Note) -
Abandoned
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Abstract
Process for the preparation of (1S, 4R)-4-hydroxy cyclopent-2-enyl esters comprising the steps of: a) reacting a cis-cyclopent-1-ene-3,5-diol, or racemic or a partially resolved 4-hydroxy cyclopent-2-enyl ester, with a suitable ester donor in the presence a lipase from Alcaligenes sp. and b) recovering and purifying the produced (1S, 4R)-4-hydroxy cyclopent-2-enyl ester. The reaction is preferably carried out at a temperature in the range from 10.degree. C. to room temperature.
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