Primer extension methods for detecting nucleic acids
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United States of America Patent
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Issued Date -
Jun 10, 2004
app pub date -
Feb 5, 2003
filing date -
Jun 16, 1997
priority date (Note) -
Abandoned
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Abstract
Methods are provided for selective nucleic acid sequence detection in single base primer extension reactions of high sensitivity. These methods are useful for detecting small amounts of mutant nucleic acid in a heterogeneous biological sample. These methods are particularly useful for identifying individuals with gene mutations indicative of early colorectal cancer.
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