Aqueous suspension eyedrops and process for producing the same
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United States of America Patent
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Issued Date -
Jun 10, 2004
app pub date -
Feb 2, 2004
filing date -
Feb 16, 2001
priority date (Note) -
Abandoned
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Abstract
An ophthalmic aqueous suspension preparation to serve as a cure for corneal herpes infection contains 9-[(2-hydroxyethoxy)methyl]guanine as an active ingredient and exhibits an improved stability. Specifically, the ophthalmic aqueous suspension preparation contains 0.2 to 5% by weight of 9-[(2-hydroxyethoxy)methyl]guanine or a pharmaceutically acceptable salt thereof, 0.05 to 1% by weight of a partially saponified product of polyvinyl acetate, and 0.01 to 1% by weight of a nonionic surfactant and has a pH of 6 to 8. Preferably, the fine crystals have a short axis of 50 .mu.m or less and a long axis of 70 .mu.m or less in length and have a ratio of the long axis to the short axis of 10:1 or less.
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