Method for monitoring biotechnological processes
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United States of America Patent
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Issued Date -
May 20, 2004
app pub date -
Oct 3, 2003
filing date -
Apr 5, 2001
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a method for monitoring biotechnological processes involving microorganisms, said method being characterized in that both the process medium and the microorganisms are directly spectroscoped in said medium by means of attenuated total reflection (ATR) at an ATR crystal whereby microorganisms come at least to a distance from the ATR crystal which corresponds to the evanescent field's depth of penetration, IR spectroscopy being carried out during this time interval, thereupon the microorganisms-containing medium being removed from the ATR crystal which then is washed and its contact is optionally renewed with the microorganisms-containing process medium, and moreover the invention relates to apparatus with which to carry out said method.
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