Detection of methylated dna molecules
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United States of America Patent
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Issued Date -
May 6, 2004
app pub date -
Oct 20, 2003
filing date -
Nov 13, 2000
priority date (Note) -
Abandoned
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Abstract
A method for detecting presence of a target DNA in a sample, the method comprising: (a) treating a sample containing DNA with an agent that modifies unmethylated cytosine; (b) providing to the treated sample a detector ligand capable of binding to a target region of DNA and allowing sufficient time for a detector ligand to bind to a target DNA; and (c) measuring binding of the detector ligand to DNA in the sample to determine the presence of the target DNA in a sample.
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