Novel method for identifying antibacterial compounds
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United States of America Patent
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Issued Date -
May 6, 2004
app pub date -
Oct 9, 2001
filing date -
Apr 9, 1999
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a method for identifying an antagonist or inhibitor of the expression of a gene encoding a polypeptide essential for bacterial growth or survival as well as for an antagonist or inhibitor of said polypeptide. The invention further relates to a method for improved antagonists or inhibitors. The invention also provides an antagonist or inhibitor of the activity of said polypeptide. The invention is further related to a method for producing a therapeutic agent in a composition comprising said antagonist or inhibitor. Furthermore, the invention is related to the use of the polypeptide and the antagonist or inhibitor as well as to a method to identify a surrogate marker.
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