Particulate inhalation carrier
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United States of America Patent
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Issued Date -
Apr 1, 2004
app pub date -
Oct 20, 2003
filing date -
Dec 8, 2000
priority date (Note) -
Abandoned
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Abstract
The present invention provides a particulate substrate suitable for carrying a drug for delivery, comprising a substantially crystalline core and a surface coating, wherein the particulate substrate has a proportion of amorphous character of 2% of greater by weight of particulate substrate, and a process for the production of carrier particles comprising the steps of: a) mixing crystalline particles having an average diameter greater than 10 .mu.m with at least partially amorphous particles having average diameters less than 10 .mu.m; b) exposing the mixture to conditions capable of inducing crystallization of the amorphous particles for a predetermined period in order that partial crystallization takes place.
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