Use of lipopeptides in immunotherapy of HIV+ individuals
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United States of America Patent
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Issued Date -
Mar 25, 2004
app pub date -
Sep 7, 2001
filing date -
Sep 8, 2000
priority date (Note) -
Abandoned
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Abstract
The present invention provides a method for controlling viral rebound in HIV+ individuals after termination of anti-retroviral therapy, the method comprising administering to an HIV+ individual who has undergone anti-retroviral therapy that has been terminated and which HIV+ individual has a viral load of less than or equal to 10,000 copies per ml of plasma and a CD4+ level greater than or equal to 300 cells per mm.sup.3, at least one lipopeptide comprising a peptide chain of 7 to 100 amino acids which comprises at least one CTL epitope of an HIV protein and which is linked by covalent attachment, optionally via a linker moiety, to a lipid chain comprising from 8 to 20 carbon atoms.
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