Cell-detaching reactor for scaled-up inoculation of anchorage-dependent cell culture
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United States of America Patent
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Issued Date -
Mar 25, 2004
app pub date -
Jun 5, 2003
filing date -
Sep 20, 2002
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Abandoned
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Abstract
A cell-detaching reactor is provided to prepare single cell suspension for inoculation of anchorage-dependent cells between the scaled-up bioreactors, which is especially useful in a commercial-scale process. The cell-detaching reactor of the invention comprises a trypsinizing zone and a separating zone, which are separated by a screen with mesh size between the diameters of the cells and the carriers.
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