Composition and method for modulating vasculogenesis or angiogenesis
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United States of America Patent
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Issued Date -
Mar 18, 2004
app pub date -
May 16, 2003
filing date -
Sep 30, 1998
priority date (Note) -
Abandoned
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Abstract
A method for modulating vasculogenesis or arteriogenesis or angiogenesis, especially for treating heart and limb ischemia, using the core domain protein of PDGF-C, a new member of the PDGF/VEGF family of growth factors, or a homodimer or a heterodimer comprising the core domain. Also disclosed are pharmaceutical compositions comprising the core protein, nucleotide sequences encoding the protein, and uses thereof in medical and diagnostic applications.
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