Small molecule inhibitors of rotamase enzyme activity

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20040049046A1
SERIAL NO

10219887

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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This invention relates to neurotrophic N-glyoxylprolyl ester compounds having an affinity for FKBP-type immunophilins, their preparation and use as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme activity.

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Patent Owner(s)

Patent OwnerAddress
GPI NIL HOLDINGS INCWILMINGTON DE 19899

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Hamilton, Gregory S Catonsville, MD 129 1221
Steiner, Joseph P Hampstead, MD 91 894

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