Methods of immunotherapy and diagnosis
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United States of America Patent
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Issued Date -
Mar 11, 2004
app pub date -
Nov 26, 2002
filing date -
Dec 11, 2001
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Abandoned
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Abstract
Certain cells, including types of cancer cells such as T-cell lymphoma, T-cell leukemia, multiple myeloma, and chronic myeloid leukemia, B cell lymphoma of mature B cell lineage, non-Hodgkin's lymphoma of mature B-cell lineage, and Burkitt's lymphoma of mature B cell lineage, are capable of expressing SEQ ID NO: 2 or 4-ecoding RNA. Immunotargeting using SEQ ID NO: 2 or 4 polypeptides, nucleic acids encoding for SEQ ID NO: 2 or 4 polypeptides and anti-SEQ ID NO: 2 or 4 antibodies provides a method of killing or inhibiting that growth of cancer cells that express the SEQ ID NO: 2 or 4 protein. Methods of immunotherapy and diagnosis of disorders associated with SEQ ID NO: 2 or 4 protein-expressing cells, such as T-cell lymphoma, T-cell leukemia, multiple myeloma, and chronic myeloid leukemia, B cell lymphoma of mature B cell lineage, non-Hodgkin's lymphoma of mature B-cell lineage, and Burkitt's lymphoma of mature B cell lineage, are described.
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