Nucleotide and amino acid sequences relating to respiratory diseases and obesity
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United States of America Patent
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Issued Date -
Mar 4, 2004
app pub date -
Oct 11, 2002
filing date -
Oct 11, 2001
priority date (Note) -
Abandoned
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Abstract
This invention relates to ADAM and Interactor genes which are associated with various diseases, including asthma. The invention also relates to the nucleotide sequences of these genes, isolated nucleic acids comprising these nucleotide sequences, and isolated polypeptides or peptides encoded thereby. The invention further relates to vectors and host cells comprising the disclosed nucleotide sequences, or fragments thereof, as well as antibodies that bind to the encoded polypeptides or peptides. Also related are ligands that modulate the activity of the disclosed genes or gene products. In addition the invention relates to methods and compositions employing the disclosed nucleic acids, polypeptides or peptides, antibodies, or ligands for use in diagnostics and therapeutics for asthma and other diseases.
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