Distinguishing molecular forms
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Issued Date -
Feb 26, 2004
app pub date -
Jun 12, 2003
filing date -
Jul 11, 2000
priority date (Note) -
Abandoned
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Abstract
A method for detecting aggregation or polymerization of molecules in a sample, which method comprises the steps of: a) exposing a sample containing the molecules to at least two labelling moieties which will bind to only a single mutually exclusive site on each of the said molecules; and b) determining whether multiply-bound labelling moieties are present. The method is particularly of use in differentiating pathogenic aggregated protein molecules from non-pathogenic, non-aggregated protein molecules.
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