Method for detection of inflammatory processes
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United States of America Patent
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Issued Date -
Feb 5, 2004
app pub date -
Dec 6, 2002
filing date -
Dec 11, 2001
priority date (Note) -
Abandoned
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Abstract
The present invention is based on the surprising observation, that a high degree of expression of certain distinct Genes in peripheral blood mononuclear cells is associated with in inflammatory process with a higher probability than it is the case for other Genes. Therefore, the present invention provides a method for diagnosis of an inflammatory process comprising monitoring expression levels of 4-6 selected targets in peripheral blood mononuclear cells as compared to expression levels of said selected targets in peripheral blood mononuclear cells in healthy individuals, characterized in that over-expression or repression of the majority of said selected Genes is indicative for an inflammatory process.
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