Apparatus and method for determining and/or monitoring electrophysiological properties of ion channels
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United States of America Patent
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Issued Date -
Feb 5, 2004
app pub date -
Jun 19, 2002
filing date -
Jun 20, 2001
priority date (Note) -
Abandoned
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Abstract
An apparatus and method for determining and/or monitoring electrophysiological properties of ion channels of ion-channel containing structures uses AC driven location electrodes to drive objects for analysis to a measurement site. The measurement site may comprise an aperture between two solution-containing compartments, each compartment containing a respective measurement electrode. The aperture includes an adhesion region at its periphery and is dimensioned so that the object for analysis cannot pass through the aperture. Alternatively, the measurement site may comprise a measurement electrode surrounded by an adhesion region appropriately dimensioned to receive the object, to which the object may adhere, and a second measurement electrode remote therefrom.
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