Bacterial carboxypeptidase cpg2 variants and their use in gene directed enzyme prodrug therapy
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United States of America Patent
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Issued Date -
Jan 22, 2004
app pub date -
Jun 9, 2003
filing date -
May 8, 2000
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Abandoned
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Abstract
The present invention relates to bacterial carboxypeptidases for use in gene directed prodrug therapy, in particular for use in the treatment of disease, including tumors. Specifically, the invention relates to modified bacterial carboxypeptidases which have enhanced catalytic activity.
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