Method for enhancing DNA base-calling accuracy
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United States of America Patent
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Issued Date -
Dec 11, 2003
app pub date -
Jun 7, 2002
filing date -
Jun 7, 2002
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Abstract
One embodiment of the present invention relates to a method of treating data derived from a separation of a nucleic acid sample. The data, which include features indicating the presence of different nucleic acid fragments in the sample are transformed on the basis of spacings between the features to obtain transformed data having a substantially constant spacing between features. Another embodiment of the present invention relates to an electrophoresis separations apparatus having at least one separation volume, a detector, and a processor. The processor is configured to transform the separations data based upon the spacing between features to obtain transformed data having a substantially constant spacing between features.
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