Sulfonamide derivatives of 3-substituted imidazol[1,2-d]-1,2,4-thiadiazole-s and 3-substituted-[1,2,4] thiadiazolo[4,5-a] benzimidazole as inhibitors of fibrin cross-linking and transglutaminases
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United States of America Patent
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Issued Date -
Dec 4, 2003
app pub date -
Mar 27, 2003
filing date -
Mar 28, 2002
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Abandoned
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Abstract
A method of inhibiting the activity of transglutaminases containing a cysteine residue comprising administering to a mammal an effective amount of a sulfonamide derivative of imidazo[1,2-d]-1,2,4-thiadiazoles sufficient to inhibit the activity.
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