Specific autoimmune reactions against isomerised/optically inverted epitopes: application for treatment of autoimmune diseases

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United States of America Patent

SERIAL NO

10367571

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Abstract

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Methods and compositions for therapeutic or prophylactic treatment of an autoimmune disease by the selective suppression of autoimmune activity against an auto-antigen, which activity involves immunological reactivity with an epitope containing an isomerised peptide linkage and/or an optically inverted amino acid comprise the use of a protein or peptide or analogue thereof containing an epitope recognised by an auto-reactive immune system component involved in said condition, which epitope contains an isomerised peptide linkage and/or an optically inverted amino acid or comprising a compound which immunologically mimics a said protein or peptide.

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Patent Owner(s)

Patent OwnerAddress
NORDIC BIOSCIENCE A/S2730 HERLEV

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Christgau, Stephan Gentofte, DK 50 320
Cloos, Paul AC Kobenhavn, DK 3 6

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