Matrix-type device for the transdermal delivery of testosterone applied to the non-scrotal skin
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United States of America Patent
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Issued Date -
Nov 20, 2003
app pub date -
May 17, 2002
filing date -
May 17, 2002
priority date (Note) -
Abandoned
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Abstract
The present invention relates to a matrix-type device for the transdermal delivery of testosterone comprising (i) a matrix layer containing a) a therapeutically effective amount of testosterone or the salt thereof, b) an adhesive polymer, and c) a penetration enhancer comprising N-methylpyrrolidone and oleoylsarcosine, and, (ii) a backing layer of polyurethane. The device of the present invention is applicable to a non-scrotal skin as compared with a known matrix-type device for the transdermal delivery and has an excellent skin-adhesion and has less tendencies of crystallizing testosterone.
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