Systems and methods to facilitate multiple order combinatorial chemical processes
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United States of America Patent
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Issued Date -
Nov 13, 2003
app pub date -
Oct 23, 2002
filing date -
Dec 5, 2000
priority date (Note) -
Abandoned
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Abstract
A method to screen for reactive chemicals comprises the steps of configuring a set of constructs such that each construct of the set includes a pairwise combination of a chemical entity (A.sub.1-A.sub.i) of a chemical library (A) and a chemical entity (B.sub.1-B.sub.j) of a chemical library (B). The set of constructs includes essentially every possible pairwise combination of the chemical entities (A.sub.1-A.sub.i) of the chemical library (A) and the chemical entities (B.sub.1-B.sub.j) of the chemical library (B). The constructs are exposed to a given set of conditions to facilitate reactions or interactions between the chemical entity (A.sub.1-A.sub.i) and the chemical entity (B.sub.1-B.sub.j) of each construct. The constructs are screened to identify any reactions or interactions, and the chemical entity (A.sub.1-A.sub.i) and the chemical entity (B.sub.1-B.sub.j) of any constructs where reactions or interactions occurred are identified.
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