Methods for microfluidic aspirating and dispensing
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United States of America Patent
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Issued Date -
Nov 6, 2003
app pub date -
May 23, 2003
filing date -
Feb 19, 1999
priority date (Note) -
Abandoned
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Abstract
A method for actively controlling the hydraulic pressure within an aspirate-dispense system for aspirating and dispensing precise and/or predetermined quantities of fluid or reagent. The method provides an efficient pressure compensation scheme to achieve the optimal pressures for aspirating and dispensing. The optimized pressures are achieved by a series of operations of a positive displacement pump and a drop-on-demand valve of the aspirate-dispense system. Advantageously, the method increases process speed, improves reliability and accuracy, and reduces dilution and wastage of reagent.
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