Recombinant iron uptake proteins
Number of patents in Portfolio can not be more than 2000
United States of America Patent
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Issued Date -
Oct 2, 2003
app pub date -
Apr 24, 2003
filing date -
Mar 27, 2000
priority date (Note) -
Abandoned
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Abstract
Neisserial iron uptake proteins including transferrin binding protein A (TbpA) and B (TbpB) in both full length form and as immunogenic fragments are made recombinantly. A non-neisserial cell expresses a TbpA which is extracted from the cell under mild conditions and retains substantially the antigenicity of native TbpA on its surface. TbpB is also made recombinantly and both TbpA and TbpB are included in vaccine compositions.
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