HSV viral vector

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United States of America Patent

SERIAL NO

10422547

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a recombinant herpes simplex virus (HSV) viral vector genome which has substantially lost its transducing properties as a result of a DNA sequence change in the gene coding for Vmw65 protein and also comprises an expressable heterologous gene inserted into a region of the HSV genome which is non-essential for the culture of the virus, the gene being under the control of the immediate early (IE1) gene enhancer of cytomegalovirus (CMV) and to the use of the recombinant HSV genome in therapy and vaccination.

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Patent Owner(s)

Patent OwnerAddress
PRESTON CHRISTOPHER MAURICENot Provided

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Ecob-Prince, Marion Suzanne Newcastle-Upon-Tyne, GB 2 29
Preston, Christopher Maurice Glasgow, GB 4 82

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