Ribbon flow cytometry and cell sorting
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United States of America Patent
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Issued Date -
Sep 18, 2003
app pub date -
Feb 20, 2003
filing date -
Mar 14, 2002
priority date (Note) -
Abandoned
status (Latency Note)
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Abstract
A microfluidic device for sorting cells is described. The device includes an input channel, a primary channel, at least two branch channels which connect with the primary channel at a junction, and a sheath injector positioned upstream from the junction. Sample solution, which may contain a population of cells, can be entered into the input channel and hydrodynamically focused into a sample ribbon. The device employs a system for directing fluid flow, and particularly the flow of the sample ribbon, into a branch channel based on a detected cell feature. The system can employ a variety of sorting techniques to change or direct the flow of cells into a particular branch channel.
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