Reagents for improved PCR
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United States of America Patent
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Issued Date -
Sep 18, 2003
app pub date -
Dec 19, 2002
filing date -
Dec 19, 2001
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Abstract
The present invention is directed to the use of a poly-hydroxy-aryl-poly-a-cid with 3-6 ortho-hydroxy-acid moieties as an additive for a nucleic acid amplification reaction. Surprisingly, such an addition results in prevention of nonspecific primer dimer formation and thus in a more specific and sensitive PCR.
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