Method of collecting data for estimation of susceptibility to periodontal disease

Number of patents in Portfolio can not be more than 2000

United States of America Patent

APP PUB NO 20030175755A1
SERIAL NO

10300799

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Abstract

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A method is provided, which comprises examining the regulating activity of a defensin gene promoter closely associated with the expression activity of defensin, an antibacterial peptide, on the basis of the detection of a gene mutation, and estimating future susceptibility to periodontal disease. The sequence homology between DNA derived from a defensin gene promoter existing in a sample obtained from the gingival tissues of a subject and a nucleotide sequence comprising a mutation site in the promoter region, and/or compatibility in PCR amplification, are determined. Thereby a gene mutation is detected and then the site of the gene mutation is determined, so that data for the estimation can be collected.

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Patent Owner(s)

Patent OwnerAddress
SUN MEDICAL CO LTDSHIGA 524-0044

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Abiko, Yoshihiro Sapporo-shi, JP 2 3
Arakawa, Toshiya Sapporo-shi, JP 13 73
Kaku, Tohru Sapporo-shi, JP 2 3
Kusano, Kaoru Sapporo-shi, JP 3 6
Nishimura, Michiko Ebetsu-shi, JP 2 3
Takuma, Taishin Sapporo-shi, JP 2 3

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