New amphetamine derivatives, antibodies against them and pharmaceutical compositions containing them
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United States of America Patent
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Issued Date -
Sep 11, 2003
app pub date -
Jan 23, 2002
filing date -
Jan 23, 2002
priority date (Note) -
Abandoned
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Abstract
Hapten-carrier conjugates capable of eliciting anti-hapten antibodies in vivo to amphetamines are disclosed. Methods of preparing the hapten-carrier conjugates and therapeutic compositions are also disclosed. A therapeutic composition containing the hapten-carrier conjugate is useful in the treatment of addiction to amphetamines. Passive immunization using antibodies raised against conjugates of the instant invention also is disclosed. The therapeutic composition is suitable for co-therapy with other conventional drugs for treatment of amphetamine abuse.
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