Extended release pharmaceutical tablet of metformin
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United States of America Patent
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N/A
Issued Date -
Sep 11, 2003
app pub date -
Dec 4, 2002
filing date -
Dec 4, 2001
priority date (Note) -
Abandoned
status (Latency Note)
Importance
Abstract
The invention provides an extended release pharmaceutical tablet containing: (i) a core comprising by weight, based on the core weight, about 70% to about 99% metformin and pharmaceutically acceptable excipients; and (ii) a coating permeable to metformin. The extended release tablet of the invention exhibit a dissolution profile such that after about 2 hours, from about 7% to about 60% of the metformin is released; after about 4 hours, from about 15% to about 90% of the metformin is released; after about 8 hours, from about 50% to about 100% of the metformin is released; after about 12 hours, more than about 75% of the metformin is released.
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