Base-modified enzymatic nucleic acid

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United States of America Patent

SERIAL NO

10170864

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Abstract

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Method to produce a more active ribozyme by introducing a modified base into a substrate binding arm of the ribozyme or its catalytic core.

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Patent Owner(s)

Patent OwnerAddress
RIBOZYME PHARMACEUTICALS INC2950 WILDERNESS PLACE BOULDER CO 80301

International Classification(s)

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  • 2002 Application Filing Year
  • C07H Class
  • 2961 Applications Filed
  • 539 Patents Issued To-Date
  • 18.21 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances200220032004200520062007200820092010201120122013201420152016201720180255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Beigelman, Leonid Longmont, CO 390 10741
Karpeisky, Alex Boulder, CO 18 578
McSwiggen, James Boulder, CO 332 8520
Usman, Nassim Boulder, CO 82 3245

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  • 1 Citation Count
  • C07H Class
  • 8.55 % this patent is cited more than
  • 22 Age
Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges29179632315114411901 - 1011 - 2021 - 3031 - 4041 - 5051 - 6071 - 8081 - 9091 - 100100 +0102030405060708090100110120130140150160170180190

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