Unsaturated 1-amino-alkylcyclohexane NMDA, 5HT3, and neuronal nicotinic receptor antagonists
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United States of America Patent
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Dec 7, 2004
Grant Date -
Sep 4, 2003
app pub date -
Nov 6, 2002
filing date -
Nov 7, 2001
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Expired
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Abstract
Unsaturated 1-Amino-alkylcyclohexane compounds which are systemically-active as NMDA, 5HT.sub.3, and nicotinic receptor antagonists, pharmaceutical compositions comprising the same, method of preparation thereof, and method of treating CNS disorders which involve disturbances of glutamatergic, serotoninergic, and nicotinic transmission, treating immunomodulatory disorders, and antimalaria, antitrypanosomal, anti-Borna virus, anti-HSV and anti-Hepatitis C virus activity.
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