Uses of synthetic peptides corresponding to telopeptide sequences of cross-linked type I collagen metabolites
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United States of America Patent
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Jul 12, 2005
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app pub date -
Mar 7, 2003
filing date -
Nov 6, 1987
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Abstract
Peptides synthesized to match the human α1 (I) and α2 (I) amino-telopeptide sequences of type I collagen degradation products in body fluids, preferably either Asp-GIu-Lys-Ser-Thr-Gly-Gly (SEQ ID NO:5) or Gln-Tyr-Asp-Gly-Lys-Gly-Val-Gly (SEQ ID NO:6). used as calibrators and antigens in immunoassays for detecting type I collagen degradation products in body fluids.
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