Method for the complete chemical synthesis and assembly of genes and genomes
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United States of America Patent
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Issued Date -
Sep 4, 2003
app pub date -
Dec 17, 2002
filing date -
Sep 16, 1997
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Abstract
The present invention relates generally to the fields of oligonucleotide synthesis. More particularly, it concerns the assembly of genes and genomes of completely synthetic artificial organisms. Thus, the present invention outlines a novel approach to utilizing the results of genomic sequence information by computer directed gene synthesis based on computing on the human genome database. Specifically, the present invention contemplates and describes the chemical synthesis and resynthesis of genes defined by the genome sequence in a host vector and transfer and expression of these sequences into suitable hosts.
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