Method for selection and agents useful for same
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United States of America Patent
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Issued Date -
Aug 28, 2003
app pub date -
Jul 26, 2002
filing date -
Jul 27, 2001
priority date (Note) -
Abandoned
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Abstract
The present invention relates generally to a method for the selection of a modified nucleic acid molecule and to agents useful for same. More particularly, the present invention relates to a method for counterselecting nucleic acid molecules which have undergone targeted modification. The method of the present invention is useful, inter alia, for rapidly and accurately selecting correctly modified nucleic acid molecules, such as modified bacterial artificial chromosomes. The present invention is also directed to counterselection cassettes for use in the method of the invention and to modified nucleic acid molecules selected thereby.
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