Antitumor agents
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United States of America Patent
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Issued Date -
Aug 21, 2003
app pub date -
Dec 9, 2002
filing date -
Aug 22, 1997
priority date (Note) -
Abandoned
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Abstract
An antitumor agent, which is a combination of an oxidoreductase, such as xanthine oxidase chemically conjugated to a polymer such as poly ethylene glycol, for initial administration and accumulation in the tumor tissue followed by administration and of a substrate for the oxidoreductase which releases reactive oxygen species. Improved tumor selective cytotoxic activity results.
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